Alptekin Aksan, PhD
Dr. Aksan is currently an Associate Professor in the Department of Mechanical Engineering at the University of Minnesota. He received his B.S. and M.S. degrees in Mechanical Engineering from the Middle East Technical University in Ankara, Turkey. He completed his Ph.D. studies on thermomechanics of collagenous tissues in Michigan State University, Mechanical Engineering Department. He worked for three years as a post-doctoral researcher in Center for Engineering in Medicine in Massachusetts General Hospital, Harvard Medical School before joining the faculty of Mechanical Engineering in University of Minnesota. His research interests are Biothermodynamics, Biostabilization, and Bioheat/mass Transfer.
Peter Dosa, PhD: Dr. Dosa is a Research Assistant Professor in the Department of Medicinal Chemistry and an Associate Program Director in the ITDD. Since arriving at UMn in 2009, his research has been focused primarily in two areas, the development of novel prodrugs to improve the pharmaceutical properties of existing medications and the design of improved drugs for CNS indications. Dr. Dosa came to UMN from Arena Pharmaceuticals, where he worked as a medicinal chemist in the drug discovery group. During the nearly seven years he was at Arena, he worked on several research projects, including those focused on developing small molecule 5-HT2A inverse-agonists as well as 5-HT2C agonists. He is a co-inventor on seven patent applications.
Allison Hubel, PhD
Dr. Hubel, BioCoR Director, is currently a Professor of Mechanical Engineering at the University of Minnesota. She is also a former faculty member in the Department of Laboratory Medicine and Pathology at the University of Minnesota. For almost 20 years, Dr. Hubel has studied both basic science and translational issues behind cell and tissue preservation (liquid storage and cryopreservation). Her research focuses on development of protocols for cell and tissue preservation, development of tools to improve preservation, and understanding molecular mechanisms of damage and education/training in the field of preservation. She has published numerous articles related to cell and tissue preservation and has been awarded three patents related to cell preservation technology.
Diane Kadidlo received her B.S. from Iowa State University. She has over 19 years experience in cell and tissue manufacturing, regulationa nd quality assurance. She has served as the Supervisor for the University of Minnesota Medical Center Clinical Cell Therapy Laboratory since 1996 overseeing the production of cell and tissue productions in support of the University of Minnesota's Blood and Marrow Transplant Program. Currently she is the Director of the UMN's Mollecular and Cellular Therapeutics Facility and plays a key role in coordinating the transfer of cell and tissue engineering methods from the laboratory bench to clinical trial while ensuring compliance with the FDA's Good Manufacturing Practices/Good Tissue Practices.
David McKenna, M.D
Dr. McKenna is an Associate Professor in the University of Minnesota Medical School. He is also the Scientific and Medical Director of Molecular & Cellular Therapeutics, the cGMP facility of the University of Minnesota, the Director of the Cell Therapy Laboratory of the University of Minnesota Medical Center and the Director of the Division of Transfusion Medicine in the Department of Laboratory Medicine and Pathology. Dr. McKenna is actively involved with the National Heart, Lung, & Blood Institute (NHLBI)-sponsored PACT (Production Assistance for Cellular Therapy) group. He is a member of AABB having served as the Chair of their Cellular Therapies Committee from 2006-2009 and currently serving as the Vice-Chair of the newly formed Cellular Therapies Section Coordinating Committee, the International Society for Cellular Therapy, the International Society for Stem Cell Research, Tissue Engineering/Regenerative Medicine-International Society, and the American Society of Hematology. He is also a Scientific Member of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative Cellular Therapy Team. His interests include umbilical cord blood research, quality assurance/quality control in cellular therapy, and translational research/clinical scale-up of biotherapeutics.
Ian M. Pope, Ph.D, MBA, BSc: Director of Business Development, Cryo Associates, Gaithersburg MD.
Ian has worked in the area of crygenic systems for over 25 years, initially as managing director of Planer PLC, the original manufacturer of controlled rate freezers. He later ran the BioMedical Division of MVE/Chart, the worlds largest provider of cryogenic storage freezers and liquid distribution systems and co-owned Core Crylab a unique biorepository, cord blood bank and international consulting group in Toronto, Canada. Ian works with and consults for many of the major repository operations in the US and aborad and sits on the ISBER standards and accreditation committee. His expertise lies in the area of the practical application of cryogenics to the storage and preservation of biological materials, the design, operation, accreditation, validation and best practices of bio-repositories and in the enviornmental and sustainability aspects of cold space provision.
Fran Rabe has over 20 years of experience working in the areas of tissue and cell quality assurance and regulatory compliance. She currently oversees the quality assurance aspect of operations at the University of Minnesota Molecular and Cellular Therapeutics (MCT) Facility, a GMP facility that manufactures standard and IND hematopoietic products, pancreatic cellular products and active pharmaceutical ingredients. Fran has extensive experience with audits, having performed in excess of 50 GMP audits at multiple U.S. and international institutions. She also has extensive experience with FDA IND submissions and working directly with FDA as it relates to the regulation of cellular and tissue products. In addition to holding a Masters Degree in Manufacturing Systems, Ms. Rabe is an American Society for Quality (ASQ) Certified Quality Manager.
Amy P.N. Skubitz, PhD
Dr. Skubitz is a Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota where she serves as the Director of the Academic Health Center's BioNet Tissue Procurement Facility. She has been a member of the International Society for Biological and Environmental Repositories (ISBER) since 1999 where she has served as a member of ISBER's Education and Training Committee for 5 years; serving as an Associate Editor of the "Best Practices for Repositories". Professor Skubitz's research is focused on biomarkers for ovarian cancer, which relies heavily upon her expertise in high quality accural, processing, and preservation of human tissues, cells, and fluids. During the past 30 years, Professor Skubitz has published over 100 manuscripts and book chapters.
Christine Wendt, MD
Dr. Wendt is an Associate Professor in the Department of Medicine at the University of Minnesota and Director of the O-Brien Biobank whose specialty is identifying biomarkers of lung disease using state-of-the-art proteomics.